My advice is always use UASP with USB 3.0 devices on the Pi 4, otherwise you're missing out on a pretty substantial performance gain. Also, remember to plug USB 3.0 devices into the blue USB 3.0 ports, not into the black USB 2.0 ports, otherwise you won't see any of the performance difference.

As we can see the default Linux disk encryption implementation has a significant impact on our cache latency in worst case scenarios, whereas the patched implementation is indistinguishable from not using encryption at all. In other words the improved encryption implementation does not have any impact at all on our cache response speed, so we basically get it for free! That’s a win!